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stilbestrol
(redirected from stilboestrol)

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stil·bes·trol (stl-bstrôl, -trl)
n.
DES.
stilbestrol.
stilbestrol
a synthetic estrogen used in the treatment of female animals for infertility and bitches for urinary incontinence. Its use as a growth promotant, especially in cattle, has been discontinued because of fears that it is a carcinogen. Its use is also not without toxicity hazards.
Overfeeding of stilbestrol as a growth promotant causes poisoning characterized by relaxation of pelvic ligaments, elevation of the tailhead, susceptibility to pelvic fracture and hip dislocation and prolapse of rectum and vagina. In castrated males there is a tendency for obstructive urolithiasis to occur. Pigs also show anuria, kidney enlargement and thickening of the ureters.
See also diethylstilbestrol, estrogen.
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This flawed science has resulted, for instance, in the drug diethylstilboestrol or stilboestrol, a synthetic ostrogen for checking cancer of the prostrate and preventing miscarriages but was found to cause transplacental cancer twenty years after the drug was first marketed (pp.
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No cases of the cancer had been reported since Stilboestrol, which was used to prevent miscarriages and was blamed for causing the cancer, was banned in the 1970s.
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Thirty years ago Stilboestrol, a drug which was used to prevent miscarriages, was blamed for causing the cancer.
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