statin


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statin

(stăt′n)
n.
Any of a class of lipid-lowering drugs that reduce serum cholesterol levels by inhibiting a key enzyme involved in the biosynthesis of cholesterol.

statin

–statin

A popular term for a HMG-CoA reductase inhibitor, which ↓ cholesterol–eg, pravastatin, lovastatin, etc, which ↓ progression of ASHD/CAD, even in absence of ↑ cholesterol. See Atorvastatin, Cervastatin, Fluvastatin, Lovastatin, Pravastatin, Simvastatin.

statin

(stat'in) [ -stat + -in]
Any of the drugs of the class known as 3-hydroxy-3-methylglutaryl coenzyme A (HMG CoA) reductase inhibitors. These drugs have powerful lipid-lowering properties. The names of drugs in this class all end in “-statin” (e.g., atorvastatin, pravastatin, rosuvastatin, and simvastatin). Drugs from this class reduce the risk of myocardial infarction and stroke. Synonym: HMG CoA enzyme inhibitor

Patient discussion about statin

Q. husband has horrible rash bil. below knees to his ankles. it is bright red yellow weeping cracks. On statins He has been on zocor for 15 years and we are so afraid this may have something to do with this drug. He has stopped taking the drug because the pain and weakness, and numbness in his legs is considerable

A. i looked up for side effects and i saw only "eczema" as a skin side effect. but it seems odd to me that after 15 years you got this kind of side effect. it should have appeared years ago. you know- it might be a very good idea to go and see a Dr... and not stopping a medication without warning..

More discussions about statin
References in periodicals archive ?
Although statins have been shown to significantly lower heart disease and stroke rates, studies estimate that of the 25-50% of patients with cardiovascular disease who stop taking their statin medications as directed, 60% cite muscle pain as the primary reason for discontinuation.
While this suggestive evidence is not strong enough to warrant routinely prescribing statins to cirrhosis patients, it does highlight the need to prescribe a statin to any cirrhosis patient who qualifies for the drug by standard criteria because of established cardiovascular disease or as part of primary prevention when there is elevated cardiovascular risk, Dr.
So instead, statin researchers report the relative risk, which suggests that 30 to 50% of the population benefit from statins.
Whether statin therapy is as effective in women as in men is debated, especially for primary prevention.
The statin and cancer excitement took off with Nielsen's November 2012 study, which reported that people in Denmark who took statins had a lower risk of dying from cancer than non-statin users.
After adjusting for factors such as demographics, medications and other co-morbidities, researchers concluded that 34% of statin users developed cataracts, compared to just 10% of people not taking the drug.
Accordingly, the current study examined whether statin use was associated with new diagnoses of dementia.
Patients who stopped taking fat-soluble statins such as simvastatin were 58% more likely to develop Parkinson's than those who stayed on them.
High-potency statin treatment was defined as [greater than or equal to]10 mg rosuvastatin, [greater than or equal to]20 mg atorvastatin, and [greater than or equal to]40 mg simvastatin; all other statin treatments were defined as low potency.
The study looked at high versus low potency statin use to eliminate a confounding factor inherent in any study of health risk among high cholesterol populations, that people to whom statins are prescribed are more likely to have "multiple comorbidities.
The number one weapon against cholesterol used by doctors are the statin drugs (e.