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neutrophil |
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neutrophil /neu·tro·phil/ (noo´tro-fil) 1. a granular leukocyte having a nucleus with three to five lobes connected by threads of chromatin, and cytoplasm containing very fine granules; cf. heterophil. 2. any cell, structure, or histologic element readily stainable with neutral dyes. rod neutrophil , stab neutrophil one whose nucleus is not divided into segments.
Neutrophil The primary type of white blood cell involved in inflammation. Neutrophils are a type of granulocyte, also known as a polymorphonuclear leukocyte. neutrophil [no̅o̅′trəfil] Etymology: L, neuter + Gk, philein, to love a polymorphonuclear, granular leukocyte that stains easily with neutral dyes. The nucleus stains dark blue and contains three to five lobes connected by slender threads of chromatin. The cytoplasm contains fine, inconspicuous granules. Neutrophils are the circulating white blood cells essential for phagocytosis and proteolysis by which bacteria, cellular debris, and solid particles are removed and destroyed. A neutrophil count less than or equal to 500 may be life-threatening. See also basophil, eosinophil, granulocyte, polymorphonuclear leukocyte. neutrophil, n a polymorphonuclear leukocyte (PMN). See also leukocyte, polymorphonuclear (PMN). neutrophil 1. one of the three granular leukocytes having a nucleus with three to five lobes connected by threads of chromatin, and cytoplasm containing lysosomes that stain characteristically and enable neutrophils to be distinguished from basophils and eosinophils; called also a granulocyte or polymorphonuclear leukocyte. See also heterophil (1). 2. any cell, structure or histological element readily stainable with neutral dyes. band neutrophil see stab neutrophil (below). neutrophil chemotactic factor see chemotactic factor. hypersegmented neutrophil increased number of nuclear lobes; seen in hyperadrenocorticism or during treatment with corticosteroids, and in blood that has been in transit for long periods. hyposegmented neutrophil a lack of nuclear lobes; may occur in chronic infections and is a feature of pelger-huet anomaly. neutrophil:lymphocyte ratio correlates directly with the magnitude of the total leukocyte count in response to disease in domestic animals; it varies from 0.5 in cattle to 3.5 in dogs. stab neutrophil a neutrophilic leukocyte whose nucleus is not divided into segments. toxic neutrophil one with blue-black or large reddish cytoplasmic granules and diffuse cytoplasmic basophilia and vacuolation; caused by disruption of maturation. neutrophil A phagocytic WBC, normally constituting 60-70% of circulating WBCs. See Band, Dysplastic neutrophil, Hypersegmented neutrophil, Polymorphonuclear neutrophil. How to thank TFD for its existence? Tell a friend about us, add a link to this page, add the site to iGoogle, or visit webmaster's page for free fun content. |
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