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squamous intraepithelial lesion

   Also found in: Acronyms, Encyclopedia, Wikipedia 0.02 sec.
Squamous intraepithelial lesion (SIL)
A term used to categorize the severity of abnormal changes arising in the squamous, or outermost, layer of the cervix.
Mentioned in: Cervical Cancer, Pap Test

squamous intraepithelial lesion
Cytology A term that encompasseses a spectrum of noninvasive cervical epithelial abnormalities–eg, flat condyloma, dysplasia/carcinoma in situ, CIN; the Bethesda Classification divides SILs into low-grade and high-grade lesions; the former encompass cellular changes associated with HPV cytopathic effect–koilocytotic atypia and mild dysplasia; high-grade lesions encompass moderate dysplasia, severe dysplasia, carcinoma in situ/CIN2–3. Cf CIN, High-grade squamous intraepithelial lesion, Low-grade squamous intraepithelial lesion, Pap smear.


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