Allele-specific rpoB PCR assays for detection of rifampin-resistant Mycobacterium tuberculosis in sputum smears
Policy message: All clinically suspected and X-ray positive but sputum smear
negative cases should undergo sputum culture for Mycobacterium tuberculosis on Lowenstein-Jensen medium.
Assessment of physical conditions and current practice in laboratories carrying out sputum smear
microscopy in Northwest Ethiopia.
A total of 1691 presumptive TB cases were enrolled in this study, but only 257 were having sputum smear
positive pulmonary tuberculosis.
After 4 months of treatment, the boy's sputum smear
microscopy and culture results remained negative, so the continuation phase of treatment was initiated.
Key words: Pulmonary tuberculosis, close contacts, sputum smear
Identifying pulmonary tuberculosis in patients with negative sputum smear
Before availability of the Xpert MTB/RIF test, the diagnosis of pulmonary TB in resource-limited settings was based primarily on detection of acid-fast bacilli by sputum smear
Change in the bacteriological status of sputum from initial acid-fast bacilli (AFB) positive to AFB negative after intensive phase (IP) of treatment is known as sputum smear
With the exception of patient 1, who remained sputum-smear and culture positive, the other 4 patients' sputum smears
converted to negative after 18-435 days, and cultures converted after 28-218 days.
PGC was associated with more extensive lung disease, lung cavitation, and positive sputum smear
at the baseline.
These included: type of entry in SINAN (new TB case: no prior TB diagnosis; relapse--completed a previous TB treatment; return after default: individuals that defaulted from a previous TB treatment regimen and returned to continue treatment), site of TB at presentation (pulmonary, extra-pulmonary, pulmonary and extra-pulmonary), tuberculin skin test result, existence of chest X-ray suspicious for TB, result of initial sputum smear
test, result of initial culture examination and second month smear, result of initial histopathological examination, and whether they received directly observed therapy (DOT).