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spinobulbar

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spinobulbar /spi·no·bul·bar/ (spi″no-bul´ber) pertaining to the spinal cord and medulla oblongata.
spi·no·bul·bar (spn-blbr, -bär)
adj.
Relating to the medulla oblongata and the spinal cord.
spinobulbar [spi″no-bul´bar]
pertaining to the spinal cord and medulla oblongata.
spinobulbar
pertaining to the spinal cord and medulla oblongata.
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While the details of how the transported toxic tail harms the Purkinje cell nucleus still need to be worked out, the basic process may more closely resemble what occurs in Huntington Disease as well as spinocerebellar ataxia types: SCA1, SCA3, SCA17, spinobulbar muscular atrophy, SCA17 and dentatorubropallidoluysian atrophy.
SCA6: a tail about a tail: the following is a research summary of a ... by Generations
Multiple (see text) SBMA, spinobulbar muscular atrophy; DRPLA, Dentatorubral-pallidoluysian atrophy; MJD, Machado-Joseph disease: DMPK, myotonic dystrophy protein kinase; DMAHP, myotonic dystrophy associated homeobox protein: DMWD, myotonic dystrophy WD repeat motif containing protein.
The Second International Conference on Unstable Microsatellites and ... by Bidichandani, Sanjay I. / Generations
During the last ten years, identical mutations (expansion of a CAG repeat encoding glutamine) were found to cause other inherited neurodegenerative disorders, the so-called "polyglutamine diseases": spinobulbar muscular atrophy (SBMA, also known as Kennedy's disease), Huntington's disease (HD), dentatorubral pallidoluysian atrophy (DRPLA), SCA3 .
Molecular pathogenesis of spinocerebellar ataxia type 1 (SCA1): ... by Servadio, Antiono / Generations
 
 
 
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