, as illustrated in Figure 4, tend to grow in a compact cohesive fashion surrounded by a dense reticulin framework; epithelioid cells grow less cohesively and are not surrounded by a network of reticulin; and mixed-cell-type tumors are composed of a mixture of the 2 cell types, as shown in Figure 5, A and B.
LMS mimics spindle-cell tumors or other sarcomas in metastasizing by a hematogenous route, mostly to the lung and liver (30 to 50%); regional lymphatic involvement tends to be a late phenomenon.
On first inspection this may, as in our case, initially be labeled as a spindle-cell tumor.
According to Barbara Forney, VMD, a practicing veterinarian and medical writer, cisplatin frequently is prescribed by equine veterinarians as a chemotherapy drug to treat equine skin tumors such as sarcoids, spindle-cell tumors
, squamous-cell carcinoma and melanoma.
These spindle-cell tumors
were originally described in the pleura and peritoneum.