After taking a thorough medical and dental history along with a detailed general and local examination, the painful swelling was differentially diagnosed to be a benign lipoma, a sebaceous cyst, an epidermoid cyst or a spindle cell lipoma
Important differential diagnoses of spindle cell lipoma
include atypical lipomatous tumor and dedifferentiated liposarcoma.
Cellular angiofibroma: A benign neoplasm distinct from angiomyofibroblastoma and spindle cell lipoma
The histologic differential diagnosis includes spindle cell lipoma
, nuchal-type fibroma, and fibromatosis.
In the histopathological examination, spindle cell lipoma
shows short stubby nuclei, ropey collagen, and variable proportions of fat.
Microscopic examination revealed a spindle cell lipoma
, with no evidence of malignancy.
Clinically and morphologically, cellular angiofibroma can simulate other benign tumours like leiomyoma, angiomyofibroblastoma, spindle cell lipoma
and perineurioma (1, 5).
Spindle cell lipoma
of the oral cavity: report of a case.
Several variants described include angio-lipoma, chondroid lipoma, myo-lipoma, spindle cell lipoma
, pleomorphic lipoma, fibrolipoma, osteolipoma/chondrolipoma, mylelipoma, adenolipoma, perineural lipoma, myxoid lipoma.
The entities we are going to discuss include classic examples, such as spindle cell lipoma
, and the relatively recent or rare entities such as medallion-like dendrocyte hamartoma (plaquelike [CD34.
The differential diagnosis of AMF includes Bartholin's gland cyst, as in our case, smooth muscle tumors, peripheral nerve sheath tumors, glomus tumor, chondroid syringoma, myxoid malignant fibrous histiocytoma, angiomyolipoma, spindle cell lipoma
and myxoid liposarcoma.
The spindle cell variant has similar histologic features of a spindle cell lipoma
(bland spindle cells, ropy collagen, interspersed mast cells, and mature fat cells) with admixed multivacuolated cells.