Clinically and morphologically, cellular angiofibroma can simulate other benign tumours like leiomyoma, angiomyofibroblastoma, spindle cell lipoma and perineurioma (1, 5).
Cellular angiofibroma: a benign neoplasm distinct from angiomyofibroblastoma and spindle cell lipoma.
In the text by Allen, spindle cell lipoma was found 11 times in 87 000 accessions.
Several cases of spindle cell lipoma in the oral cavity have been reported.
Angiomyofibroblastoma like tumor of the male genital tract; analysis of 11 cases with comparison to female angiomyofibroblastoma and spindle cell lipoma
The present tumor can be distinguished readily from myxoid variants of malignant fibrous histiocytoma, liposarcoma, neurofibroma, epithelioid leiomyoma, and spindle cell lipoma through conventional histologic and immunohistochemical evaluation.
2,5,6,8] Based on the analysis of 11 cases of male AMFB, Laskin et al proposed the view that the male AMFB-like tumors, including spindle cell lipoma, encompass a broad spectrum of soft-tissue neoplasms, presumably originating from perivascular stem cells that may potentially undergo myofibroblastic differentiation.
Other lesions to be included in the histologic differential diagnosis are solitary myofibroma, fibrous histiocytoma, desmoid tumor, and spindle cell lipoma
Spindle cell lipoma is strongly CD34 positive: an immunohistochemical study.
26-29] Occasional positivity has been described in benign nerve sheath tumors, epithelioid sarcomas, and spindle cell lipomas.
Spindle cell lipoma
was first described by Enzinger and Harvey in 1975 as a variant of the typical benign lipoma.
Spindle cell lipomas
(SCLs) are an uncommon variant of lipoma.