sphingolipid


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sphingolipid

 [sfing″go-lip´id]
a phospholipid containing sphingosine (e.g., ceramides, sphingomyelins, gangliosides, and cerebrosides), occurring in high concentrations in the brain and other nerve tissue.

sphin·go·lip·id

(sfing'gō-lip'id),
Any lipid containing a long-chain base like that of sphingosine (for example, ceramides, cerebrosides, gangliosides, sphingomyelins); a constituent of nerve tissue.

sphingolipid

/sphin·go·lip·id/ (sfing″go-lip´id) a lipid in which the backbone is sphingosine or a related base, the basic unit being a ceramide attached to a polar head group; it includes sphingomyelins, cerebrosides, and gangliosides.

sphingolipid

(sfĭng′gə-lĭp′ĭd, -lī′pĭd)
n.
Any of a group of lipids, such as the ceramides, that yield sphingosine or its derivatives upon hydrolysis. They are major components of cell membranes and play a role in signaling and regulatory functions.

sphingolipid

[sfing′gōlip′id]
Etymology: Gk, sphingein, to bind, lipos, fat
a compound that consists of a lipid and a sphingosine. It is found in high concentrations in the brain and other tissues of the nervous system, especially membranes.

sphin·go·lip·id

(sfing'gō-lip'id)
Any lipid containing a long-chain base like that of sphingosine (e.g., ceramides, cerebrosides, gangliosides, sphingomyelins); a constituent of nerve tissue.

sphingolipid

fatty constituent of nerve tissue

sphingolipid

one of the two dominant 'families' of lipids; a range of phospholipids containing sphingosine (e.g. ceramides, sphingomyelins, gangliosides and cerebrosides), occurring in high concentrations in the brain and other nerve tissue.
References in periodicals archive ?
An introduction to sphingolipid metabolism and analysis by new technologies.
ELOVL1 is a ubiquitously expressed gene, the product of which was thought to be associated with synthesis of C24 sphingolipids (Tvrdik et al.
We next investigated the predictive value of sphingolipid metabolism on major adverse cardiovascular events (MACE), a summation of readmission caused by AMI, unstable angina, heart failure, malignant arrhythmia, or sudden cardiac death, in the AY group after discharge; a total of four patients had MACE at the 1-year follow-up.
It revealed that GBE could restore fatty acid metabolism, sphingolipid metabolism, phospholipid and glyceride metabolism, energy metabolism and amino acid metabolism.
Sphingolipids, including sphingosine-1-phosphate, have been shown to function as signaling mediators to regulate diverse aspects of plant growth, development, and stress response (Zhang et al.
Mechanism of action of sphingolipids and their metabolites in the toxicity of fumonisin B1.
1991) Secretion of sphingolipid hydrolase activator precursor, prosaposin.
Dysregulation of sphingolipid and sterol metabolism by ApoE4 in HIV dementia.
This finding prompted the researchers to investigate whether sphingolipid production is connected to asthma.
gamma-Tocopherol or combinations of vitamin E forms induce cell death in human prostate cancer cells by interrupting sphingolipid synthesis.
FB can disrupt sphingolipid metabolism, which plays a role in membrane and lipoprotein structure and in cell regulation as second messengers for growth factors, differentiation factors, and cytokines (Abdel-Wahhab et al.