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spherocytosis

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spherocytosis /sphe·ro·cy·to·sis/ (sfēr″o-si-to´sis) the presence of spherocytes in the blood.
hereditary spherocytosis  a congenital hereditary form of hemolytic anemia characterized by spherocytosis, abnormal fragility of erythrocytes, jaundice, and splenomegaly.
spher·o·cy·to·sis (sfîr-s-tss, sfr-)
n.
The presence of spherocytes in the blood.
spherocytosis
[sfir′ōsītō′sis]
the abnormal presence of spherocytes in the blood. Compare elliptocytosis.
spherocytosis [sfe″ro-si-to´sis]
the presence of spherocytes in the blood.
hereditary spherocytosis a congenital hereditary form of hemolytic anemia characterized by spherocytosis, abnormal fragility of erythrocytes, jaundice, and splenomegaly.
spherocytosis
the presence of spherocytes in the blood.
spherocytosis
Congenital spherocytic anemia, congenital spherocytosis, hereditary spherocytosis, spherocytic anemia Hematology A rare–1:5000 AD condition characterized by chronic hemolytic anemia with ↑ osmotic fragility and autohemolysis of globose RBC due to various defects in RBC membrane proteins Clinical Infants may be jaundiced; other Sx may be seen in older Pts fatigue, weakness, SOB, anemia, intermittent jaundice, splenomegaly, gallstones, leg ulcers Management Splenectomy. Cf Elliptocytosis.
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hereditary spherocytosis or RBC coated with antibodies) is not able to transverse the sinusoidal network and is then phagocytosed and destroyed by macrophages.
Drug-induced haemolytic anaemia by Sinxadi, Phumla; Maartens, Gary / CME: Your SA Journal of CPD
A A peripheral blood osmotic fragility test has traditionally been considered important in the workup of hereditary spherocytosis (HS).
Utility of osmotic fragility test by Baer, Daniel M. / Medical Laboratory Observer
Arran was born with a rare blood condition, spherocytosis.
ARRAN NETS GOAL by Huddersfield Daily Examiner (Huddersfield, England)
 
 
 
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