spherocyte


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Related to spherocyte: spherocytosis, target cell

spherocyte

 [sfēr´o-sīt]
a small, globular, completely hemoglobinated erythrocyte without the usual central pallor, found in hereditary spherocytosis and acquired hemolytic anemia. adj., adj spherocyt´ic.

sphe·ro·cyte

(sfē'rō-sīt),
A small, spheric red blood cell.
[sphero- + G. kytos, cell]

spherocyte

/sphe·ro·cyte/ (sfēr´o-sīt) a small, globular, completely hemoglobinated erythrocyte without the usual central pallor characteristically found in hereditary spherocytosis but also in acquired hemolytic anemia.spherocyt´ic

spherocyte

[sfir′əsīt]
Etymology: Gk, sphaira, sphere, kytos, cell
an abnormal spherical red blood cell with a high cytoplasm-to-membrane ration. In Wright-stained peripheral blood films, spherocytes are dense, lack central pallor, and have a reduced diameter. Spherocytes appear most frequently in warm autoimmune hemolytic anemia and hereditary spherocytosis. spherocytic, adj.

sphe·ro·cyte

(sfēr'ō-sīt)
A small, spheric red blood cell.
[sphero- + G. kytos, cell]

spherocyte

a small, globular, completely hemoglobinated erythrocyte without the usual central pallor; characteristically found in some types of acquired hemolytic anemia, particularly immune-mediated.
References in periodicals archive ?
It is well known that erythrocytes change into spherocytes by a substantial loss of membrane surface through vesiculation and MV generation.
A peripheral blood smear from the patient had 1 or 2 schistocytes and 1 or 2 spherocytes per high-power field, a typical platelet morphology, and hyperlobated neutrophils.
Section II discusses the specifics of grading individual red blood cell abnormalities and defines a grading system described in words and images for anisocytosis, poikilocytosis, microcytosis, macrocytosis, hypochromia, polychromasia, blister cells, target cells, teardrop cells, schistocytes, sickle cells, spherocytes, acanthocytes, echinocytes, elliptocytes, stomatocytes, Howell-Jolly bodies, basophilic stippling, Pappenheimer bodies, rouleaux, and agglutination.
Interestingly, it has long been held that automated hematocrit results will be one percent to three percent less than the microhematocrit results when abnormal cells such as sickle cells, macrocytes, hypochromic cells, and spherocytes are present because of the effect of trapped plasma in the micro-centrifuge method.
However, no spherocytes or nucleated RBCs were seen in the peripheral smear; rather, a few teardrop cells were present.
Notably, the presence of spherocytes (hemolysis), teardrop cells (myelofibrosis, bone marrow metastases), or sickle cells (sickle-cell anemia), as examples, give information beyond that of the standard indices.
The red cell morphology showed anisocytosis, poikilocytosis with occasional teardrop cells, spherocytes, ovalocytes, and a few schistocytes.