sperm antibodies

sperm antibodies

Any of a group of antibodies produced against four distinct components of spermatozoa (sperm cells). While sperm antibodies are linked to infertility, they do not cause a particular disease; they may be found in the circulation (either free or as immune complexes), in semen and/or attached to the sperm surface.
 
Ref range/normal
IgA, IgG, IgM < 15% binding.
References in periodicals archive ?
Presence of sperm antibodies and association with viscosity of semen.
Effect of sperm antibodies on pregnancy outcome in a subfertile population.
Relationship of sperm antibodies in women and men to human in vitro fertilization, cleavage, and pregnancy rate.
Sperm must be present in sufficient volume, they must be active, they must not clump together, they must be relatively normal in shape and size and they must not be adversely affected by sperm antibodies either in the man or woman.
Detection of sperm antibodies in the semen was also performed by direct method immediately after collection.
1,2] Thus, sperm antibodies detected on the sperm surface or in the cervical mucus play a definite role in fertility.
The role of sperm antibodies in the inhibition of sperm penetration into cervical mucus has been clearly defined.
The presence of sperm antibodies in serum is not closely correlated with the presence of sperm antibodies in cervical mucus in a given individual.
There are numerous methods for determining sperm antibodies.
12] In further studies of relevant sperm antibodies involved in human infertility, the relevant sperm cell antigens should be identified and characterized.
Sperm antibodies, immunoglobulins, and complement in human follicular fluid.