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spectinomycin

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spectinomycin /spec·ti·no·my·cin/ (spek″tĭ-no-mi´sin) an antibiotic derived from Streptomyces spectabilis, used as the hydrochloride salt in the treatment of gonorrhea.
spectinomycin [spek″tĭ-no-mi´sin]
an antibiotic derived from Streptomyces spectabilis, used as the hydrochloride salt in treatment of gonorrhea.

spectinomycin
an aminocyclitol antibiotic derived from Streptomyces spectabili; the hydrochloride is used as a feed additive for swine and chickens.


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Standard fastidious anaerobe agar (FAA) supplemented with bovine blood (10%), spectinomycin (400 [micro]g/mL), and polymyxin B (5 [micro]g/mL) was determined empirically to be the optimal medium for isolation of spirochetes.
Antibiotic resistance decreased for ampicillin by 60%, chorlamphenical by 57%, erythromycin by 43%, neomycin by 38%, oxytetracycline by 40 %, spectinomycin by 64%, streptomycin by 29%, tetracycline by 48%, and vancomycin by 7%.
When the scientists silenced whiB7 in that microbe within human cells growing in the lab, the mutant strain became 10 times as sensitive to spectinomycin as the normal strain was, the researchers reported in the Aug.
 
 
 
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