sotalol


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sotalol

 [so´tah-lol]
a non-cardioselective beta-adrenergic blocking agent, used as the hydrochloride salt in treatment of life-threatening ventricular arrhythmias.

sotalol

/so·ta·lol/ (so´tah-lol) a non-cardioselective beta-adrenergic blocking agent used as the hydrochloride salt in the treatment of life-threatening cardiac arrhythmias.

sotalol

(sō′tə-lôl′, -lōl′)
n.
A beta-blocker drug, C12H20N2O3S, used in its hydrochloride form to treat certain cardiac arrhythmias.

sotalol

[so′tah-lol]
a noncardioselective beta-adrenergic blocking agent, used as the hydrochloride salt in treatment of life-threatening ventricular arrhythmias.

Betapace AF

A racemic mixture of d- and l-sotalol, with beta-blocking (class II) and cardiac action potential duration prolongation (class-III antiarrhythmic properties).

Adverse effects
Fatigue, bradycardia, proarrhythmia, dyspnea, diarrhoea, nausea, vomiting, QT-interval prolongation, nonspecific increase in liver enzymes.

sotalol

Betapace®, Sotacor® Cardiology A class II beta blocker that ↑ myocardial action potential duration, ↑ cardiac refractory period, lengthens QT interval; sotalol is used for conduction block, A Fib, torsade de pointes, angina, HTN, suppress PVCs, ventricular tachyarrhythmias Adverse effects Proarrhythmia due to ↑ β blockade; it may aggravate pre-existing arrhythmias–eg, sinus bradycardia, provoke new arrhythmias–eg, torsade de points–±2.5%, exacerbate CHF, hypotension, bronchospasm, fatigue, dizziness, dyspnea, headache. See β-blocker, SWORD.

sotalol

A long-acting beta-blocker drug used to treat irregularity of the heart action. Brand names are Beta-Cardone and Sotacor.
References in periodicals archive ?
A cardiologist at Waitemata District Health Board provided an opinion to the coroner on September 30, 2010, in which he stated "it must be considered likely that the inadvertent administration of Sotalol accelerated Mr Ward's already accepted demise.
Torsade de pointes with sotalol overdose treated successfully with lidocaine.
Treatment most commonly uses beta blockers and sotalol while amiodarone may be used as an add-on therapy.
Three studies looked at propranolol, one study at sotalol, one study at atenolol, one study at bucindolol, and one study at atenolol, metoprolol, and pindolol.
With these patients, drugs on Class 1, 2 and 4 should also be avoided) amiodarone, biaxin chloral hydrate, cocaine as local chloroquine, indapamide, lithium, anaesthetic, dexatrine, chlorpromazine serevent, ventolin, dobutamine, dopamine, cisaprid, zithromax ephedrine, epinephrine, clarithromycin, levophed, appetite disopyramide, suppressant phentermine, domperidone, haldol, dexatrim[R], acutrim[R], mellaril, methadone, sibutramine, ritilin, procainamide, ventolin sotalol Class 1: Drugs that Class 4: Drugs that are weakly are accepted by associated with TdPand/or QT authorities to have prolongation but are unlikely to be a risk of prolonging a risk for TdP when used in usual QT interval and TdP recommended dosages and in patients without other risk factors *.
23) Interestingly, the only other therapeutic agents that have been shown to achieve a similar reduction in atrial fibrillation after heart surgery have been the beta-blocker class of antihypertensive drugs such as metoprolol, anti-arrhythmic medications like sotalol, (24) and the anti-arrhythmic drug, amiodarone.
If albuterol is attached to the b receptor, the smooth muscle relaxation can be fully reversed by a b-blocking agent such as propranolol or sotalol, indicating a competitive blockade.
Comparison of beta-blockers, amiodarone plus beta-blockers, or sotalol for prevention of shocks from implantable cardioverter defibrillators: the OPTIC Study: a randomized trial.
Sotalol hydrochloride is the active ingredient in Betapace AF, a treatment for irregular heart rhythms made by Schering AG unit Berlex Inc.
If the digoxin/propranolol combination still does not work, stop them both and consider the use of third-line medications such as flecainide or sotalol.
Q I AM 70 years of age and take Isotard and Sotalol tablets for my heart condition.