SON

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SON

A gene on chromosome 21q22.11 that encodes an RNA-binding protein which acts as a mRNA splicing cofactor by promoting efficient splicing of cell cycle and DNA-repair transcripts (e.g., TUBG1, KATNB1, TUBGCP2, AURKB, PCNT, AKT1, RAD23A and FANCG), which possess weak splice sites. SON also binds to DNA and may indirectly repress hepatitis-B virus (HBV) core promoter activity, as well as transcription of HBV genes and production of HBV virions.
References in periodicals archive ?
4) sonship by vocation (the case of a human becoming a Son mainly as a result of human initiative).
There is, obviously, a double sonship here, represented by the "Sons of God" and the "Sons of the Logos.
Actually, the Philonic text mentioned above is "the first formulation of such a double theory of sonship," which is only later found implicitly in Rom.