SON

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SON

A gene on chromosome 21q22.11 that encodes an RNA-binding protein which acts as a mRNA splicing cofactor by promoting efficient splicing of cell cycle and DNA-repair transcripts (e.g., TUBG1, KATNB1, TUBGCP2, AURKB, PCNT, AKT1, RAD23A and FANCG), which possess weak splice sites. SON also binds to DNA and may indirectly repress hepatitis-B virus (HBV) core promoter activity, as well as transcription of HBV genes and production of HBV virions.
References in periodicals archive ?
Usually the noisy, annoying, question asking sons of bitches are the ones that get into this kind of business.
Sons of bitches, can a woman being raped keep quiet?
In a doleful article for the Los Angeles Times Magazine, novelist Paco Ignacio Taibo II wondered aloud: "Are these sons of bitches eternal?
All of you who are into drugs, you sons of bitches, I will really kill you," Duterte said during his election in April.
Another was more brutal: "ISIS is ready to cut off your heads, dear Americans, O sons of bitches.
Killer biker and surf-inspired rock-n-roll from the original line up of grizzled, truck-drivin' sons of bitches and snake handlers--always a good time.
Strapped to the ground at one point, with buckets of creepy crawlies tipped over her, she called Ant and Dec jerkoffs, d**kheads and sons of bitches, giving them the finger throughout the whole ordeal.