SON

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SON

A gene on chromosome 21q22.11 that encodes an RNA-binding protein which acts as a mRNA splicing cofactor by promoting efficient splicing of cell cycle and DNA-repair transcripts (e.g., TUBG1, KATNB1, TUBGCP2, AURKB, PCNT, AKT1, RAD23A and FANCG), which possess weak splice sites. SON also binds to DNA and may indirectly repress hepatitis-B virus (HBV) core promoter activity, as well as transcription of HBV genes and production of HBV virions.
References in periodicals archive ?
wouldn't turn up the heat on them as long as they were regarded as anti-communist--as "sons of bitches, but our sons of bitches.
Fuck all you sons of bitches with your Hot Topic mall bullshit.
Usually the noisy, annoying, question asking sons of bitches are the ones that get into this kind of business.