SON

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SON

A gene on chromosome 21q22.11 that encodes an RNA-binding protein which acts as a mRNA splicing cofactor by promoting efficient splicing of cell cycle and DNA-repair transcripts (e.g., TUBG1, KATNB1, TUBGCP2, AURKB, PCNT, AKT1, RAD23A and FANCG), which possess weak splice sites. SON also binds to DNA and may indirectly repress hepatitis-B virus (HBV) core promoter activity, as well as transcription of HBV genes and production of HBV virions.
References in periodicals archive ?
He was brotherly, he was sonly, he was fatherly, he was comfortable, he
Gulf fritillary feed only on passion vines, and monarchs sonly to milkweed.
Sonly has five IC suppliers, including Broadcom(AMD), NXP, Trident, MediaTek and NEC, of which, Trident and NEC are the majors.