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1. to expose to sound waves; to disrupt bacteria by exposure to high-frequency sound waves.
2. the products of such disruption.


To expose a suspension of cells or microbes to the disruptive effect of the energy of high frequency sound waves.


(sŏn′ĭ-kāt) [L. sonus, sound]
To expose to sound waves.


1. to expose to sound waves; to disrupt bacteria by exposure to high-frequency sound waves.
2. the products of such disruption.

Patient discussion about sonicate

Q. do you know what are the pros and cons of the Sonic toothbrush from Oral B (electric tooth brush)? last night, my best friend raved about it for a whole hour. My dentist told me to use a soft brush (number 35) to clean my teeth and that the electric brushes are a bit over rated. My friend specifically told me about the Sonic product and told me that it also makes his teeth whiter. I wanted to know if anybody has any knowledge or experience from first hand about this product or any good information about it.

A. Thank you for the frank answer. I wonder if I can find a really soft electric toothbrush

More discussions about sonicate
References in periodicals archive ?
proposed a 2-tiered EIA approach consisting of 2 FDA-cleared EIAs: whole-cell sonicate EIA followed by reflex C6 EIA.
miyamotoi (30), no data are available that examined the potential cross-reactivity of whole-cell sonicate or C6 B.
Since the cross-reacting material is PorA, it is present in sufficient quantity in bacterial sonicates used in the direct ELISA for all strains to be positive.
Extraction Extraction First water Sample type solvent (a) method addition Air filter 5 mL x 2 Sonicate 100 mL Air PUF 30 mL x 4 Squeeze 80 mL Impactor plate 5 mL x 2 Sonicate 100 mL Impactor filter 10 mL x 2 Sonicate 100 mL Surface wipe 20 mL x 2 Sonicate 360 mL PUF roller sleeve 150 mL x 4 Squeeze 150 mL Floor dust (bulk) 25 mL Sonicate 100 mL Hexane Second water Sample type partition addition Air filter 20 mL x 2 100 mL Air PUF 20 mL x 2 70 mL Impactor plate 20 mL x 2 100 mL Impactor filter 20 mL x 2 100 mL Surface wipe 20 mL x 2 0 mL PUF roller sleeve 25 mL x 2 0 mL Floor dust (bulk) 20 mL x 2 80 mL Variation in standard procedure, scaled to size of sample matrix.
The SONOPULS model homogenizers sonicate volumes from 50 ml up to 11 on a batch basis.
burgdorferi by using a whole-cell sonicate ELISA, C6 ELISA, or Western blot assay as described (16,20-22).
Immunoaffinity chromatographic isolation of a high molecular weight seroreactive protein from Mycobacterium leprae cell sonicate.
Th2-type immune response observed in healthy individuals to sonicate antigen prepared from the most prevalent Mycobacterium tuberculosis strain with single copy of IS6110.
9%) to dissolve and sonicate for about 5 min, dilute to volume with methanol and mix.
For preparation of triton-soluble extracts, the sonicate from each sample was diluted with 1x PBS containing protease inhibitor and Triton X-100 (Loba Chemie, Mumbai, India) (1% final concentration) up to 200 [micro]l at 5 [micro]g/[micro]l protein concentration and mixed thoroughly for complete solubilization (12).
Samples obtained from these patients were tested by a commercial enzyme-linked immunosorbent assay (ELISA) (PanBio, East Brisbane, Queensland, Australia) for the presence of immunoglobulin (Ig) A against a Bordetella pertussis sonicate and by an in-house IgA-detection ELISA directed against pertussis toxin as previously described (9).
GSTA1-1 was purified from the bacterial sonicate by gel filtration on Sephadex G50 (Pharmacia) followed by affinity chromatography on S-hexylglutathione (35) coupled to epoxy-activated Sepharose 6B (Pharmacia).