In clinical trials, the most common adverse reactions (5% greater than placebo) for the highest recommended doses of Neupro([R]) for treatment of Parkinson's disease were nausea, vomiting, somnolence
, application site reactions, dizziness, anorexia, hyperhidrosis, insomnia, peripheral edema, and dyskinesia.
Special Considerations: The most common side effects included somnolence
, anorexia, dizziness, and nausea.
At points in this recounting, Boyer sits in an SUV in a rainstorm, looking fatuously reflective as his deliberate, monotonous voice-over narration, ponderously slow to the point of somnolence
, metes out the facts.
In the 12-week, controlled study in patients with PHN, somnolence
and dizziness were the most frequently reported side effects.
The most common adverse reactions (>5% and >1% higher than placebo) include dizziness, somnolence
, fatigue, irritability, falls, nausea, weight gain, vertigo, ataxia, headache, vomiting, contusion, abdominal pain, and anxiety.
Among the adverse events reported in at least 5% of the patients taking the combination, weight gain, increased appetite, dry mouth, somnolence
, and fatigue were reported at twice the rate of events in patients who received placebo.
concluded that treatment-emergent adverse events, including anorexia, nausea, somnolence
, dizziness, and vomiting, were significantly more common among those taking atomoxetine.
The headache causes somnolence
, one sign of a subdural hematoma.
In practical terms, the finding might lead to new, more efficient medications to treat insomnia and somnolence
, Reiner said.
The IRLS Scale contains 10 items designed to assess the severity of sensory and motor symptoms, sleep disturbance, daytime somnolence
, and impact on activities of daily living and mood associated with RLS.
Use of BANZEL has been associated with central nervous system-related adverse reactions, such as somnolence
or fatigue, coordination abnormalities, dizziness, gait disturbances, and ataxia.
In the 4-week aripiprazole study, the most common adverse effects that were observed in at least 5% of those in the two aripiprazole-treated groups combined and that were at least twice the rate observed among those on placebo were somnolence