somatotroph

somatotroph

 [so-mat´o-trof″]
a type of acidophil of the adenohypophysis that secretes growth hormone.

so·mat·o·troph

(sō-mat'ō-trōf),
A cell of the adenohypophysis that produces somatotropin.

somatotroph

/so·mato·troph/ (-trōf″) a type of acidophil of the adenohypophysis that secretes growth hormone.

so·ma·to·troph

, somatotrope (sō-mat'ō-trōf, -trōp)
A cell of the adenohypophysis that produces somatotropin.

somatotroph

any of the cells of the adenohypophysis that secrete growth hormone.
References in periodicals archive ?
GH is synthesized and stored by somatotroph cells within the anterior pituitary gland.
In this paper, we reported a male patient who had acromegaly, probably secondary to a pituitary somatotroph adenoma but now has hypopituitarism with secondary adrenal insufficiency and hypopituitarism.
Proliferation of lactosomatotroph GH3 and somatotroph MtT/S rat pituitary cells as well as of corticotroph AtT20 mouse pituitary cells was inhibited by curcumin in monolayer cell culture and in colony formation assay in soft agar.
Melamed et al [106] suggest that estradiol and IGF-I, both generated from cells other than the somatotrophs, may exert antiapoptotic effects and thus possibly control the size of this somatotroph cells.
However, during aging there is evidence of declining activity of the GH/IGF-I axis, which is mainly dependent on age-related variations in the hypothalamic control of somatotroph function (somatopause).
Octreotide acetate is a synthetic somatostatin analogue that binds to somatostatin receptors on somatotroph tumors and inhibits GH synthesis and secretion.
Even variants derived from a single cell type can be distinguished; for example, the subtypes of somatotroph adenomas are conveniently recognized with the application of keratin stains because sparsely granulated somatotroph adenomas are characterized by scant GH immunoreactivity and conspicuous fibrous bodies that are stained by the CAM 5.
Ghrelin: a step forward in the understanding of somatotroph cell function and growth regulation.
Regulation of pituitary somatotroph differentiation by hormones of peripheral endocrine gland.
In patients with GHD, who have few responsive somatotroph cells, the conversion factor was also applicable, suggesting that the relative concentration of the 22-kDa form during peak GH responses to the PD-GHRH test remained the same regardless of the number of somatotroph cells.