IGF1

(redirected from somatomedin-C)

IGF1

A gene on chromosome 12q23.2 that encodes a protein, similar to insulin in structure and function, which belongs to a family of proteins involved in mediating growth and development.

Molecular pathology
IGF1 mutations are a cause of insulin-like growth factor I deficiency.
References in periodicals archive ?
Buyume hormonu ve somatomedin-C 'nin myeloma progresyonu uzerine olan bu olasi etkileri literatur esliginde tartisildi Turk Jem 2013; 17:75-7
Previous studies have shown that growth hormone and somatomedin-C activate B lymphocyte and somatomedin-C receptors are found in multiple myeloma cells.
Our group previously reported that zinc deficiency may affect the generation of somatomedin-C which in turn named as Insulin growth factor-1 (IGF-1) Decreased IGF-1 levels were reported by us and others in beta thalassemia major patients [3].