somatic cell nuclear transfer


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Related to somatic cell nuclear transfer: therapeutic cloning, DNA sequencing

somatic cell nuclear transfer

Cloning in which the nucleus of a somatic—i.e., non-germinal/reproductive—cell is transferred into an egg from which the nucleus has been previously removed, in order generate an embryonic stem-cell line, which has the advantage of pluripotency—i.e., the ability to differentiate along multiple pathways except the reproductive pathway

somatic cell nuclear transfer

In cloning, the transfer of genetic material from a differentiated, adult cell into an egg.
See also: transfer
References in periodicals archive ?
Effects of [beta]-mercaptoethanol on the development of murine-bovine interspecies somatic cell nuclear transfer embryos
The public policies recommended with respect to the creation of a child using somatic cell nuclear transfer reflect the Commission's best judgments about both the ethics of attempting such an experiment and our view of traditions regarding limitations on individual actions in the name of the common good.
Somatic cell nuclear transfer in its first and second decades: successes, setbacks, paradoxes and perspectives.
somatic cell nuclear transfer in the sheep induces placental defects that likely precede fetal demise.
Embryogenesis and blastocyst development after somatic cell nuclear transfer in nonhuman primates: overcoming defects caused by meiotic spindle extraction.
The efficiency for obtaining live births after somatic cell nuclear transfer technique is 10% in cattle species.
Using a technique called somatic cell nuclear transfer (SCNT), the Oregon-based researchers successfully removed the genetic material from a monkey's egg cells.
Neaves said the ultimate goal is not to create therapies with somatic cell nuclear transfer, the practice of placing the nucleus of an ordinary body cell in the cytoplasm of an egg to create a stem cell.
3) As a matter of fact, we do not know at this point which of the possible sources of disease-specific pluri-potent human stem cells--genetically screened IVF embryos, iPS cells, somatic cell nuclear transfer into enucleated oocytes, (4) or somatic cell chromosome transfer into zygotes and blastomeres that have had their own chromosomes removed (5)--will prove to be the best for clinical applications, all other things considered.
Tong quickly dismisses concerns about asking women to provide eggs for the cloning technique known as somatic cell nuclear transfer (SCNT)--a high-profile aspect of stem-cell research, but one that is still very much speculative.
These two patents are part of a portfolio of patents and patent applications owned by Roslin Institute that are directed to foundational somatic cell nuclear transfer cloning technology developed at Roslin Institute for the cloning of Dolly the sheep.
Lanza, who joined ACT in 1999, developed and managed several of the company's human embryonic stem cell research programs including the Retinal Pigment Epithelial Cell Program, the Hemagioblast Cell Program and the Somatic Cell Nuclear Transfer research.