soluble fms-like tyrosine kinase 1

soluble fms-like tyrosine kinase 1

,

sFlt-1

An antiangiogenic protein found in the serum of women who subsequently develop preeclampsia. It may contribute to the development of this syndrome.
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Statins, meanwhile, have been shown to prevent or reverse angiogenic imbalance by promoting the release of vascular endothelial growth factor and placental growth factor and by suppressing the production of soluble FMS-like tyrosine kinase 1 and soluble endoglin.
Excess placental soluble fms-like tyrosine kinase 1 (sFlt1) may contribute to endothelial dysfunction, hypertension, and proteinuria in preeclampsia.
First trimester placental growth factor and soluble fms-like tyrosine kinase 1 and risk for preeclampsia.
Soluble fms-like tyrosine kinase 1 (sFlt1), endoglin and placental growth factor (PlGF) in preeclampsia among high risk pregnancies.
Diagnostic utility of soluble fms-like tyrosine kinase 1 and soluble endoglin in hypertensive diseases of pregnancy.
Prevalence of agonistic autoantibodies against the angiotensin II type 1 receptor and soluble fms-like tyrosine kinase 1 in a gestational age-matched case study.
There was no association between the levels of vitamin D and of two angiogenic factors that have been previously implicated in the development of preeclampsia, soluble FMS-like tyrosine kinase 1 (sFlt-1) and placental growth factor (PlGF).
Both new studies examined pregnant women's blood concentrations of placental growth factor (PlGF) and soluble fms-like tyrosine kinase 1 (sFlt1).
Moreover, the increase in TSH level was significantly associated with increasing quartiles of soluble fms-like tyrosine kinase 1 (sFlt-1), which "may be responsible for the clinical phenotype of preeclampsia," the investigators wrote.
The gene encoding a protein called soluble fms-like tyrosine kinase 1 (sFlt1) was overactive in the preeclamptic placentas.
The rights are specific to the combined use of soluble fms-like tyrosine kinase 1 (sFlt-1) and placental growth factor (PlGF) for the diagnosis of vascular diseases.
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