soluble antigen


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sol·u·ble an·ti·gen

viral antigen that remains in solution after the particles of virus have been removed by means of centrifugation; in the case of the influenza viruses, it is the internal helical structure, free of the external envelope.
Synonym(s): S antigen (1)

soluble antigen

An antigen dissolved in a liquid. A soluble antigen is recognized by B lymphocytes but cannot be detected by T lymphocytes until it has been processed by an antigen-presenting cell. See: T cell.
See also: antigen
References in periodicals archive ?
In a previous paper we have evaluated the regulation and proliferation induced by soluble antigens of epimastigotes or trypomastigotes (24).
Systemic administration of soluble antigens is a well-accepted approach to induce immunological tolerance [12].
Even secretory antigens cannot be efficiently presented to MHC class 1 and II because of the inefficiency of internalization of soluble antigens through fluid phase pinocytosis (20).
They also showed for the first time that CD141hi DCs were superior at cross-presenting soluble antigens compared to other DCs to activate the killer T cells.
Some suppression of cell-mediated immunity occurs, and maternal lymphocytes demonstrate a diminished proliferative response to soluble antigens and to allergenic lymphocytes.