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solifenacin

   Also found in: Wikipedia 0.01 sec.
solifenacin,
an anticholinergic.
indication This drug is used to treat overactive bladder.
contraindications Uncontrolled narrow-angle glaucoma, urinary retention, gastric retention, and known hypersensitivity to this drug prohibit its use.
adverse effects Adverse effects of this drug include anxiety, paresthesia, fatigue, headache, chest pain, hypertension, abdominal pain, dry mouth, dyspepsia, dysuria, urinary retention and frequency, urinary tract infection, rash, pruritus, bronchitis, cough, pharyngitis, and upper respiratory tract infection. Common side effects include dizziness, vision abnormalities, xerophthalmia, nausea, vomiting, anorexia, and constipation.


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Anticholinergic agents such as oxybutynin, oxytrol, tolterodine, and solifenacin succinate are often used to inhibit detrusor muscle contraction.
Treatment of urge urinary incontinence with botulinum toxin A by Toth, Peter P. / Journal of Applied Research
Treatment for OAB currently consists of oral administration of compounds such as oxybutynin, tolterodine, darifenacin, solifenacin, and trospium each of which have significant side effects, including dry mouth (seen in 70% of patients), nausea, dry eyes, and constipation.
Antares Pharma Doses First Patients in Pivotal Trial of ANTUROL(TM) by Business Wire
Compared to oxybutynin, tolterodine, solifenacin and darifenacin, SVT-40776 is the most potent and selective M3 vs M2 yet developed.
SALVAT Has Completed Patient Enrollment in a Dose Finding Phase Ii ... by Business Wire
 
 
 
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