fluorescein

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fluorescein

 [floo͡-res´ēn]
a fluorescing dye; the sodium salt is used as a contrast medium in retinal angiography and as a diagnostic aid for revealing corneal lesions and fitting contact lenses.

fluor·es·ce·in

(flōr-es'ē-in), [C.I. 45350]
An orange-red crystalline powder that yields a bright green fluorescence in solution and is reduced to fluorescin; a nontoxic, water-soluble indicator used diagnostically to trace water flow.

fluorescein

/flu·o·res·ce·in/ (fldbobr-res´ēn) a fluorescing dye; its sodium salt is used as a tracer in retinal angiography and as a diagnostic aid for revealing corneal trauma and fitting contact lenses.

fluorescein

(flo͝o-rĕs′ē-ĭn, flô-, flō-)
n.
An orange-red compound, C20H12O5, that exhibits intense fluorescence in alkaline solution and is used in medicine for diagnostic purposes, in oceanography as a tracer, and as a textile dye.

fluor·es·ce·in

(flōr-es'ē-in)
[C.I. 45350] An orange-red crystalline powder that yields a bright green fluorescence in solution, and is reduced to fluorescin; a nontoxic, water-soluble indicator used diagnostically to trace water flow and to visualize corneal abrasions or ulcers.

fluorescein

A green dye that fluoresces bright yellow in blue or ultraviolet light. It is used to tag (label) and thus show up ANTIBODIES in tissues. It is also much used by eye specialists (ophthalmologists) to show up ulcers on the cornea and to delineate for photography the blood vessels of the retina. For the latter purpose, the due is injected rapidly into the bloodstream (fluorescein angiography). The drug is on the WHO official list. Brand names are fluorescein, Minims fluorescein, Minims lignocaine (lidocaine, a local anaesthetic) and fluorescein, and Minims proxymetacaine (a local anaesthetic) and fluorescein.

Fluorescein

A brand name for FLUORESCEIN.

Fluorescein

A fluorescent chemical used to examine the cornea.
Mentioned in: Corneal Ulcers

fluorescein

A fluorescent, weak dibasic acid with a molecular weight of 376 whose sodium salt is used in dilute solution as a dye in the fitting of contact lenses, in the detection of corneal abrasions, etc. It is a yellowish-red compound, which fluoresces a brilliant yellow-green under ultraviolet or blue illumination (Fig. F7). Syn. sodium fluorescein. See fluorexon; Burton lamp; Wood's light; rose bengal; staining; break-up time test; fluorescein test.
Fig. F7 Fluorescein on the corneal surface staining A, an abraded area, and B, some damaged epithelial cellsenlarge picture
Fig. F7 Fluorescein on the corneal surface staining A, an abraded area, and B, some damaged epithelial cells

fluor·es·ce·in

(flōr-es'ē-in)
Nontoxic, water-soluble indicator used diagnostically to trace water flow and visualize corneal abrasions.

fluorescein (flôres´ēin),

n in dentistry, a dye applied to teeth to reveal plaque. In ophthalmology, it is used to discover corneal lesions.

fluorescein

a fluorescing dye, an acid fluorochrome; the sodium salt is used in solution to reveal corneal lesions and as a test of circulation in the retina and extremities. The isothiocyanate derivative (FITC) is used for labeling of immunoglobulins in various immunofluorescence techniques.

fluorescein strips
sterilized applicators impregnated with fluorescein for use in ophthalmic tests.
References in periodicals archive ?
One significant adverse event was a protocol deviation in which 1 patient received an incorrect dose of IV sodium fluorescein (500 mg) instead of the recommended 25-mg dose.
In our practice, surgeons prefer that intravenous sodium fluorescein be administered just prior to cystoscopy and oral phenazopyridine en route to the operating room.
Physician satisfaction was statistically significant with the use of mannitol as a bladder distention medium over oral phenazopyridine, and satisfaction was better compared with use of IV sodium fluorescein or normal saline distention
Intravenous sodium fluorescein is routinely used in ophthalmology in retinal angiography, at a dosage of 5 mL of 10% fluorescein, he said.
Sodium fluorescein, usually termed in a clinical setting as simply 'fluorescein', has a variety of ophthalmic applications, including assessment of retinal vascular function using fluorescein angiography, Goldmann applanation tonometry (GAT), and rigid gas permeable contact lens fitting.
With sodium fluorescein dye instilled, the quality and stability of the tear film can be assessed by way of tear break-up time (TBUT), while tear osmolarity can provide additional useful information; the quantity of tears is assessed by measuring the tear meniscus height and by performing a Schirmers test.
It is currently considered essential that the patient evaluation be carried out with a slit lamp, and that the assessment should include ocular surface evaluation in the presence of sodium fluorescein (NaF1), (12) either regular (ie.
Interestingly, although sodium fluorescein (a pH indicator dye) has been widely used to assess corneal integrity since the 19th century, it is still not absolutely clear how it acts on the ocular surface.
The natural ability of sodium fluorescein to fuoresce at 510-520nm under exposure to light of wavelength 495nm (visible blue), (19) allows excellent visualisation of the dye in the eye, but not all slit lamps seem to provide this exact optimal wavelength of light.
NaFL = Sodium Fluorescein, LG = Lissamine Green UPPER MEAN (MEDIAN) LIMIT OF SCORE for non- NORMALITY FEATURE GRADING SCALE CL wearers Bulbar McMonnies 0.
Monitor every 6 months using sodium fluorescein dye

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