Although etiologies are numerous, small airways disease
may be generally divided into small airways disease
related to tobacco; to various other exposures, including mineral dusts; to diseases involving other areas of the lung, with secondary bronchiolar involvement; and to idiopathic causes.
Lung biopsy shows non-necrotizing epithelioid granulomas (Figure 1C) and small airways disease
Miller doesn't expect 100% concordance with his results, but believes the DOD-funded research will validate Vanderbilt's findings of small airways disease
COPD is a slowly developing progressive small airways disease
comprised broadly of chronic bronchitis and emphysema, and characterized by airflow limitation and decreased lung function.
For example, the FEF25-75% helps distinguish healthy smokers from healthy nonsmokers in large groups of individuals; this suggests it could be an early marker of small airways disease
Small airways disease
, subdivided into mineral dust-associated small airways disease
(11) and smoking-related small airways disease
(12,13), was identified, and exposure to cigarette smoke in the recent past was assessed on the basis of accumulation of characteristic smokers' macrophages within the respiratory bronchioles and adjacent alveoli (14,15).