ARF3

(redirected from small GTP-binding protein)

ARF3

A gene on chromosome 12q13 that encodes a protein of the ADP-ribosylation factor gene family, which encode small guanine nucleotide-binding proteins that stimulate the ADP-ribosyltransferase activity of cholera toxin and are involved in vesicular trafficking as phospholipase D activators.
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Despite the dramatic changes induced by EPEC in the cytoskeleton, there appears to be little involvement of the Rho family of small GTP-binding proteins normally involved in cytoskeletal rearrangements (29).
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