The overarehing goal is to optimally synchronize the sleep's Process C and Process S, a 2-process model of sleep regulation
which is beyond the scope of this paper but can be reviewed elsewhere.
The study concluded "BMAL1 expression in skeletal muscle is both necessary and sufficient to regulate total sleep amount and reveal that critical components of normal sleep regulation
occur in muscle.
Sleep-wake disturbances in people with cancer part I: An overview of sleep, sleep regulation
, and effects of disease and treatment.
Their results agree with the hypothesis that homeostatic sleep regulation
differs between morning types and evening types, with morning types showing indications of a higher rate of dissipation of sleep pressure during the night.
Narcolepsy is a neurological disorder of sleep regulation
that affects the control of sleep and wakefulness.
Borbely, "A two process model of sleep regulation
," Human Neurobiology, vol.
In the central nervous system TNF-[alpha] is a multipotent cytokine produced by neurons, glia, and microvascular endothelial cells that is implicated in several physiological events, such as memory consolidation and sleep regulation
Borbely AA A two process model of sleep regulation
Thus alterations in orexin levels might be related to disordered sleep regulation
observed in obese humans and animal models.
Pathways to adolescent health sleep regulation
Pathways to adolescent health: sleep regulation
According to Borbely's Two-Process Model of Sleep Regulation
(1982), sleep-wake behavior is regulated by the joint action of an exponentially increasing drive for sleep -sleep homeostasis or Process S- and by variations in sleep propensity due to a biological circadian oscillator (Process C).