The study, published in the Clinical Interventions in Aging Journal, demonstrates positive effects of the drug on cognitive performance and sleep maintenance
in the AD patients.
028) indicating beneficial effects on sleep maintenance
Sleep experts agree that insomnia is a condition of unsatisfactory sleep, either in terms of sleep onset, sleep maintenance
or early waking.
Over the five years of follow-up, shorter sleep duration and poorer sleep maintenance
were significantly associated with changes in both systolic and diastolic pressure, such that short sleep duration significantly increased the risk of hypertension.
They studied 160 white adults (97 women, 63 men) aged 30-72 years, most of whom had mixed sleep-onset and sleep maintenance
In addition, sleep maintenance
insomnia, or the inability to
The choice of medication is influenced by whether the patient is experiencing primarily sleep-onset insomnia or sleep maintenance
In both age groups, measures of sleep onset and sleep maintenance
improved significantly with eszopiclone (Lunesta), a sedative hypnotic approved by the U.
The patent relates to a class of inverse agonists to the 5-HT2A serotonin receptor, which is thought to be involved in the regulation of sleep architecture and sleep maintenance
The drug was superior to placebo in sleep latency and sleep maintenance
for transient insomnia and superior in sleep latency and total sleep time in five 6-month studies in chronic insomnia.
Periodic leg movements in sleep (PLMS), a condition that causes sudden movements that sometimes arouse sleepers, has also taken the blame as a frequent cause of poor sleep maintenance
The major effect we found with melatonin was in sleep maintenance
," says study leader Nava Zisapel of Tel Aviv University.