skip metastases

skip metastases

A discontinuous spread of malignancy in which uninvolved contiguous regions are interspersed with foci of involvement.

Examples, “skipping” cancers
Oesophageal cancer, osteosarcoma, squamous cancer of mouth.

Prognosis
Generally, dismal.

skip metastases

Discontinous metastases Oncology The metastatic spread of a CA in which contiguous regions are skipped, while distant foci of the CA are present, a finding with a poor prognosis. See Metastasis.
References in periodicals archive ?
Three patients (9%) had positive non-SLNs with negative SLNs, representing skip metastases.
The other was in a patient in whom 21 non-SLNs and 1 SLN were initially negative, representing an additional case of skip metastases recognized only by multilevel sectioning of all 21 non-SLNs.