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skeletal fluorosis

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skeletal fluorosis,
skeletal changes caused by long-term ingestion of excessive fluoride, including hyperostosis, osteopetrosis, and osteoporosis.

fluorosis [floo͡″ro´sis]
a condition due to ingestion of excessive amounts of fluorine or its compounds; see fluoride poisoning.
chronic endemic fluorosis that due to unusually high concentrations of fluoride, usually in the natural drinking water supply, typically causing dental fluorosis characterized by a mottled appearance of the teeth. Combined osteosclerosis and osteomalacia can also occur in occupational exposures to vapors and dust.
dental fluorosis hypoplasia of the dental enamel resulting from prolonged ingestion of drinking water containing high levels of fluoride, manifested by the condition called mottled enamel.
skeletal fluorosis skeletal changes due to long term ingestion of excessive fluoride; they may include hyperostosis, osteopetrosis, and osteoporosis.


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It is estimated that more than 10 million people in Guizhou Province and surrounding areas suffer from dental and skeletal fluorosis (Cao 1991; Chen et al.
This text was drafted in response and contains chapters discussing fluoride environmental occurrence, geochemistry, and exposure; human health effects; guidelines and standards; removal of excessive fluoride; analytical methods; and country data on dental and skeletal fluorosis associated with exposure to fluoride through drinking water (covering 28 countries).
The report said that in China alone, more than 10 million people suffer from skeletal fluorosis, in which fluoride accumulates in the bones progressively over many years leading to stiffness and pain in the joints and sometimes crippling changes to bone structure and calcification of ligaments.
 
 
 
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