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sitagliptin

   Also found in: Wikipedia 0.01 sec.
sitagliptin,
an oral antidiabetic.
indications This drug is used alone or in combination with other antidiabetic agents to treat type 2 diabetes mellitus.
contraindications Diabetic ketoacidosis and known hypersensitivity to this drug prohibit its use.
adverse effects Adverse effects of this drug include hypoglycemia and abdominal pain. Common side effects include headache, nausea, and vomiting.


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In this group, 2 patients regained insulin independence after treatment with the antihyperglycemic drug sitagliptin, which was associated with an increase in C-peptide levels.
DPPIV inhibitors Sitagliptin is the first DPPIV inhibitor to be approved by the FDA for use as monotherapy or together with metformin or thiozolidinediones.
The case studies of drug optimization against antitargets include the development of sitagliptin, the discovery of a way to improve an anti-anxiety medication, and new strategy and tactics for hERG optimization.
 
 
 
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