sister chromatid exchange


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sis·ter chro·ma·tid ex·change

the exchange during mitosis of homologous genetic material between sister chromatids; increased as a result of inordinate chromosomal fragility due to genetic or environmental factors. See: recombination.

sister chromatid exchange

The exchange of corresponding parts of homologous maternal and paternal chromosomes during the first meiotic division. This contributes to genetic diversity in the offspring. Synonym: crossing over
See also: exchange
References in periodicals archive ?
significant reduction in the frequency of cell with chromosomal damage and sister chromatid exchanges may be due to the antioxidant property of ascorbic acid.
Preston, Chromosome aberrations, micronuclei, aneuploidy, sister chromatid exchanges, and cancer risk assessment.
Sister chromatid exchanges in rotogravure printing plant workers.
Chromosome aberrations and sister chromatid exchanges induced by toluene diisocyanate and methylenediphenyl diisocyanate in cultured human lymphocytes.
Role of metabolism and DNA adduct formation in the induction of sister chromatid exchanges in human lymphocytes by diethylstilbestrol.
Our previous study also presented evidence for the relationship between smoking and enhanced sister chromatid exchanges in traffic policemen (27).
Sister chromatid exchanges and high frequency cells in men environmentally and occupationally exposed to ambient air pollutants, an inter-group comparison with respect to seasonal changes and smoking habit.
The ready quantifiable nature of sister chromatid exchanges with high sensitivity for revealing toxicant-DNA interaction and the demonstrated ability of genotoxic chemicals to induce significant increase in sister chromatid exchanges in cultured cells has resulted this endpoint being used as indicator of DNA damage in blood lymphocytes of individuals exposed to genotoxic carcinogens [1].
Benzene-, catechol-, hydroquinone- and phenol-induced cell transformation, gene mutations, chromosome aberrations, aneuploidy, sister chromatid exchanges and unscheduled DNA synthesis in Syrian hamster embryo cells.
chromosome aberrations, sister chromatid exchanges, cell transformations, and gene mutations in mammalian cell cultures (7-10).