Sinus histiocytosis with massive lymphadenopathy

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sinus histiocytosis with massive lymphadenopathy

A chronic disease that occurs in children and is characterized by massive painless cervical lymphadenopathy that is the result of distension of the lymphatic sinuses by macrophages containing ingested lymphocytes.

sinus histiocytosis with massive lymphadenopathy

Rosai-Dorfman disease Hematology condition most common in young blacks Clinical Massive bilateral cervical lymphadenopathy, fever, leukocytosis, ↑ ESR, polyclonal hyperimmunoglobulinemia Prognosis Uncertain; most resolve spontaneously; some are aggressive and ultimately fatal. Cf Sinus histiocytosis.

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Sinus histiocytosis with massive lymphadenopathy
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