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single-gene disorder |
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single-gene disorder Genetics A hereditary disorder caused by a mutant allele of a single gene–eg, cystic fibrosis, Duchenne muscular dystrophy, hemophilia, Huntington's disease, retinoblastoma, sickle cell disease; SGDs typically
describe classic simple Mendelian patterns of inheritance–autosomal dominant, autosomal recessive, X-linked. See Gene, Mutation. Cf Polygenic disorder. How to thank TFD for its existence? Tell a friend about us, add a link to this page, add the site to iGoogle, or visit webmaster's page for free fun content. |
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