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simian virus 40

   Also found in: Dictionary/thesaurus, Acronyms, Wikipedia 0.01 sec.
simian virus 40 (SV40),
a vacuolating virus isolated from the kidney tissue of rhesus monkeys. SV40 produces malignancy in human and newborn hamster kidney cells and tumors when inoculated into newborn hamsters.


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4-SV40 virus Some studies have raised the possibility that infection with simian virus 40 (SV40) might increase the risk of developing mesothelioma.
The virus, tentatively named Ryukyu virus 1 (RV1), caused apparent CPE on primary kidney cells derived from a Ryukyu flying fox and on our established bat kidney T1 (BKT1) cells, which were derived from the kidney of a horseshoe bat (Rhinolophus ferrumequinum) and transformed with expression plasmid DNA encoding the large T antigen of replication origin-defective simian virus 40.
Among their topics are immune surveillance in cancer, Castelan's disease, naso-pharyngeal cancer diagnosis and management, viral hepatitis and hepato-carcinogenesis, simian virus 40 and human malignancy, and abnormalities of the coagulation system associated with HIV infection.
 
 
 
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