simian virus 40
Also found in: Dictionary, Acronyms.
Related to simian virus 40: adenovirus
sim·i·an vac·u·o·lat·ing vi·rus No. 40 (SV40),
a small (40-45 nm) DNA virus of the genus Polyomavirus, family Papovaviridae; the cause of seemingly inapparent infections in monkeys, especially rhesus, and a common contaminant of monkey cell cultures; the virus may cause inapparent infection in humans and may be excreted in stools of children for several weeks; it can produce fibrosarcoma in suckling hamsters, and transformation may occur in human diploid cells; it may also form "hybrid" virus in cells also infected with certain adenoviruses.
Synonym(s): simian virus 40
simian virus 40 (SV40)
a vacuolating virus isolated from the kidney tissue of rhesus monkeys. SV40 produces malignancy in human and newborn hamster kidney cells and tumors when inoculated into newborn hamsters.