simian crease


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Related to simian crease: Down syndrome

sim·i·an crease

a single transverse palmar crease formed by fusion of the proximal and distal palmar creases, so called because of its similarity to the transverse flexion crease seen in some monkeys; a common but not pathognomonic feature of Down syndrome; also found in 1% of the normal population.

simian crease

[sim′ē·ən]
Etymology: L, simia, ape; ME, creste, crest
a single crease across the palm produced from the fusion of proximal and distal palmar creases, seen in congenital disorders, such as Down syndrome. Also called simian line.

simian crease

A dermatoglyphic pattern of a single deep transpalmar crease formed by fusion of proximal and distal palmar creases, which is classically seen in trisomy 21, but also in trisomies 13 and 9, and in foetal trimethadione syndrome. So called because of its verisimilitude to the same crease in monkeys.

simian crease

Simian fold Neonatology A dermatoglyphic pattern of a single deep transpalmar crease formed by fusion of proximal and distal palmar creases, classically seen in trisomy 21, but also in trisomies 13 and 9, fetal trimethadione syndrome. See Dermatoglyphics. Cf Triradius.
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SIMIAN CREASE: Normal palmar crease
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SIMIAN CREASE: Simian crease

simian crease

A crease on the palm of the hand, so called because of its similarity to the transverse flexion crease found in some monkeys. Normally the palm of the hand at birth contains several flexion creases, two of which are separate and approx. transverse. When these two appear to fuse and form a single transverse crease, a simian crease is present. The crease may be present in a variety of developmental abnormalities, including Down syndrome, rubella syndrome, Turner syndrome, Klinefelter syndrome, pseudohypoparathyroidism, and gonadal dysgenesis.
See: illustration
See also: crease

simian crease (sim´ēən),

n a single crease across the palm produced from the fusion of proximal and distal palmar creases, seen in such congenital disorders as Down syndrome.
References in periodicals archive ?
The court held, inter alia, that the defendants' expert medical witnesses' testimony that simian creases on the baby's hands were evidence of a prenatal injury as opposed to anything that occurred during delivery.
External examination showed low set ears, cyanosis of the lips and nailbeds, bilateral simian creases and a markedly globose abdomen.
The patient may have other associated anomalies9 which include cleft lip and/or palate, abnormal ears, hydrocephalus, cranial/spinal malformations, microphthalmus, congenital heart disease, tracheo-esophageal fistula, omphalocele, anorectal malformation, renal malformation (agenesis, polycystic kidneys), duplication of cervix or uterus, vascular anomalies, nail aplasia or dysplasia, digital anomalies, simian creases, Goltz syndrome (focal dermal hypoplasia), trisomy 13, intestinal lymphangiectasia and pyloric atresia.

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