simethicone (redirected from simeticone)

simethicone /si·meth·i·cone/ (sĭ-meth´ĭ-kōn) an antifoaming and antiflatulent agent consisting of a mixture of dimethicones and silicon dioxide.

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si·meth·i·cone (s-mth-kn)

n.

A mixture of dimethyl polysiloxanes and silica gel that is used as an antiflatulent.

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simethicone

[simeth′ikōn]

an antiflatulent that helps the gases to dissolve in liquid by decreasing the surface tension of gas bubbles.

indication It is prescribed to disperse gas pockets in the GI tract.

contraindications There are no significant contraindications other than hypersensitivity to the medication.

adverse effects There are no significant adverse effects.

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simethicone

an antiflatulent substance consisting of a mixture of dimethyl polysiloxanes and silica gel. Called also activated dimethicone.

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simethicone (simeticone)

Dentinox Colic Drops (UK), Equalizer Gas Relief, GasAid, Gas-X, Gas-X Extra Strength, Genasyme, Infacol (UK), Infantaire Gas, Maximum Strength Mylanta Gas, Mylanta Gas, Mylicon, Mylicon Infant Drops, Ovol (CA), Phazyme, Wind-Eze (UK)

Pharmacologic class: Methylated linear siloxane mixture

Therapeutic class: Antiflatulent, antifoam agent

Pregnancy risk category NR

Action

Causes gas bubbles to coalesce and allows gas to pass through GI tract via belching or passing of flatus. Silicone antifoam spreads on surface of aqueous liquids, forming a film of low surface tension that causes foam bubbles to collapse.

Availability

Capsules: 95 mg, 125 mg

Capsules (liquid-filled): 125 mg, 166 mg

Drops: 40 mg/0.6 ml, 40 mg/1 ml, 95 mg/1.425 ml

Suspension: 40 mg/0.6 ml, 50 mg/5 ml

Tablets: 60 mg, 62.5 mg, 80 mg, 95 mg

Tablets (chewable): 40 mg, 80 mg, 125 mg, 150 mg, 166 mg

⊘Indications and dosages

➣ Excess gas in GI tract after surgery or from air swallowing, dyspepsia, peptic ulcer, or diverticulitis

Adults and children older than age 12: 40 to 125 mg P.O. q.i.d. after meals and at bedtime, up to 500 mg/day

Children ages 2 to 12: 40 mg P.O. q.i.d., up to 240 mg/day

Children younger than age 2: 20 mg P.O. q.i.d.

Contraindications

• Hypersensitivity to drug
• Intestinal perforation or obstruction

Precautions

Use cautiously in:
• abdominal pain of unknown cause (especially when accompanied by fever).

Administration

• Give as needed after meals and at bedtime.

Route	Onset	Peak	Duration
P.O.	Immediate	Unknown	3 hr

Adverse reactions

None significant

Interactions

None significant

Patient monitoring

• Monitor GI status to assess drug efficacy.

Patient teaching

• Tell patient to take after meals and at bedtime as needed.
• Caution patient not to take dose higher than indicated on package unless prescriber approves.