silver sulfadiazine


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Related to silver sulfadiazine: Flamazine

silver

 [sil´ver]
a chemical element, atomic number 47, atomic weight 107.870, symbol Ag. (See Appendix 6.) It is used in medicine for its caustic, astringent, and antiseptic effects. It is also used in dentistry in alloys, in soldering, and as cones to obliterate the root canal.
silver nitrate colorless or white crystals, used as a caustic and local antiinfective; an important use is in prevention of ophthalmia neonatorum.
silver protein silver made colloidal by the presence of, or combination with, protein; an active germicide with a local irritant and astringent effect.
silver sulfadiazine the silver derivative of sulfadiazine, having bactericidal activity against many gram-positive and gram-negative organisms, as well as being effective against yeasts; used as a topical antiinfective for the prevention and treatment of wound sepsis in patients with second and third degree burns.
toughened silver nitrate a mixture of silver nitrate with hydrochloric acid, sodium chloride, or potassium nitrate, occurring as white crystalline masses molded into pencils or cones; a convenient means of applying silver nitrate locally.

sil·'ver sul·fa·di·a·zine

the silver derivative of sulfadiazine, used externally as a topical antibacterial agent in preventing and treating infections in burns.

silver sulfadiazine

a topical antibiotic.
indications It is prescribed to prevent or treat infection in second- and third-degree burns.
contraindications Known hypersensitivity to this drug, to silver, or to sulfonamides prohibits its use. It is not given in the last weeks of pregnancy or to newborn or premature infants.
adverse effects Among the most serious adverse effects are rash, fungal infection, neutropenia, and kernicterus.

sil·ver sul·fa·di·a·zine

(silvĕr sŭlfă-dīă-zēn)
Derivative of sulfadiazine, used externally as a topical antibacterial agent to prevent and treat infections in burns.

silver sulfadiazine

A drug used to treat infected leg ulcers, burns, skin graft donor sites and pressure sores (bedsores). The drug is on the WHO official list. A brand name is Flamazine.

sil·ver sul·fa·di·a·zine

(silvĕr sŭlfă-dīă-zēn)
Silver derivative of sulfadiazine, used externally as a topical antibacterial agent.

silver

1. a chemical element, atomic number 47, atomic weight 107.870, symbol Ag. See Table 6. It is used in medicine for its caustic, astringent and antiseptic effects. Experimental poisoning with silver salts causes myopathy.
2. a coat color in dogs, foxes.

silver amalgam
see amalgam.
silver collie syndrome
see canine cyclic hematopoiesis.
silver grass
aristidacontorta.
silver halide
any of the silver salts with halogens including bromine, chlorine, iodine used in photographic emulsion.
silver iodide
soluble silver salt used in cloud seeding but presents no toxicological risk to local grazing cattle.
silver-leaf ironbark
eucalyptusmelanophloia.
silver-leafed nightshade
solanumelaeagnifolium.
silver nitrate
colorless or white crystals, used as a caustic and local anti-infective.
silver nitrate (toughened)
a mixture of silver nitrate with hydrochloric acid, sodium chloride or potassium nitrate, occurring as white crystalline masses molded into pencils or cones, called caustic pencils; a convenient means of applying silver nitrate locally. Called also lunar caustic.
silver protein
silver made colloidal by the presence of, or combination with, protein; an active germicide with a local irritant and astringent effect.
silver stain
a method of demonstrating flagella on bacteria, or for visualizing very thin bacteria, such as leptospires.
silver sulfadiazine
the silver salt of sulfadiazine, having bactericidal activity against many gram-positive and gram-negative organisms, as well as being effective against yeasts; used as a topical anti-infective for the prevention and treatment of wound sepsis in patients with second and third degree burns.
silver weed

sulfadiazine

a rapidly absorbed and readily excreted sulfonamide antibacterial agent. Used commonly in triple-sulfa preparations. The sodium salt is used intravenously.

silver sulfadiazine
see silver sulfadiazine.
sodium sulfadiazine
an antibacterial compound used intravenously.
sulfadiazine-trimethoprim
a very popular combination of a potentiated sulfonamide because of its broad antibacterial spectrum and its small dose rate.
References in periodicals archive ?
Figure 4 illustrates the change in concentration of soluble silver and sulfadiazine in the chloride-containing medium SSES when a silver sulfadiazine paste was placed above the various membranes.
This demonstrated that silver sulfadiazine had dissociated, allowing the sulfadiazine to move through the membrane into the medium below, while the chloride from the medium had diffused through the membrane and reacted with the dissolved silver in the paste reservoir to form solid silver chloride and some soluble dichloroargentate(I) anion (Ag[Cl.
48 [micro]mol/L) similar to that for silver sulfadiazine.
When the two types of 10 g/kg silver sulfadiazine creams were placed above the cellulose membrane, the movement of silver varied for both creams, with the laboratory-manufactured cream showing similar results to that obtained with silver sulfadiazine paste, whereas the proprietary cream gave concentrations that were one-tenth of this value.
Figure 6 illustrates the change in concentration of soluble silver and sulfadiazine in SSES in the presence of the silver-binding ligand, glutathione (a tripeptide), when a silver sulfadiazine paste was placed above each of the various membranes.
When the same experiments were performed with silver chloride instead of silver sulfadiazine, the concentration of soluble silver was as illustrated in Fig.
When each of the two types of 10 g/kg silver sulfadiazine creams was placed above the cellulose membrane, the movement of silver and sulfadiazine across the membrane into SSES plus glutathione was much slower than that obtained with a silver sulfadiazine aqueous paste.
Figure 8 shows the change in concentration of soluble silver and sulfadiazine in human serum over a 5-day period, when silver sulfadiazine was separated from the medium by the various hydrophilic membranes.
When these same experiments were performed with silver chloride instead of silver sulfadiazine, the concentration of soluble silver in the medium (shown in Fig.
When each of the two types of 10 g/kg silver sulfadiazine creams was placed above the cellulose membrane, the movement of silver and sulfadiazine across the membrane into human serum was much slower than that obtained when silver sulfadiazine aqueous paste was used.
When either silver sulfadiazine or silver chloride is placed in direct contact with any of the media investigated, the following equilibria occur:
When silver sulfadiazine was used experimentally, this trend was clearly observed; however, the trend was not as clear with silver chloride, as chloride was not analyzed (see Figs.