castration cells

(redirected from signet ring cells)

cas·tra·tion cells

altered basophilic cells of the anterior lobe of the pituitary that develop following castration; the body of the cell is occupied by a large vacuole that displaces the nucleus to the periphery, giving the cell a resemblance to a signet ring.
Synonym(s): signet ring cells

cas·tra·tion cells

(kas-trā'shŭn selz)
Altered basophilic cells of the anterior lobe of the pituitary that develop following castration; the body of the cell is occupied by a large vacuole that displaces the nucleus to the periphery, giving the cell a resemblance to a signet ring.
Synonym(s): signet ring cells.
References in periodicals archive ?
Cytologic criteria were Nuclear morphology (Large nuclei, Anisonucleosis, Hyperchromatic nuclei, Vesicular nuclei, Chromatin clumping, Prominent nucleoli, Multiple nucleoli), and Cellular morphology (Comet cells, Signet ring cells, Vacuolar cytoplasm, Granular cytoplasm, Apocrine cells, Ractive ductal cells, Squamous cells).
The prostatic lymphomas with infiltrated lymphocytes containing a large cytoplasmic vacuole and an eccentric nucleus may also resemble signet ring cells.
An ultrasound-guided fine needle aspirate yielded only a small sample containing atypical signet ring cells, which were not diagnostic but suspicious for malignancy.
The signet ring cells within these tumors can demonstrate a plasmacytoid or monocytoid appearance or can have the classic signet ring cell morphology, characterized by a large cytoplasmic vacuole compressing the nucleus to one side of the cell.
Myxoid liposarcomas are as common as the welldifferentiated type; they are composed of proliferating lipoblasts at varying stages of differentiation, signet ring cells, a plexiform capillary pattern, and a myxoid matrix with nonsulfated glycosaminoglycans.
The tumor was composed of well-formed glands containing abundant mucin and signet ring cells.
The tumor was composed of signet ring cells within a desmoplastic stroma, displaying an Indian file pattern of infiltration (Fig.
Hematoxilin and eosin staining of these biopsies displayed islands of adenocarcinoma with signet ring cells surrounded by a desmoplastic reaction (Fig.
Lumina may mimic signet ring cells, but mucin staining will differentiate between the two.
12] SRCs are composed of signet ring cells, displaying large mucin containing intracellular vacuoles; signet ring cells are morphologically similar to UC lipoid cells.
Degenerative change with extracellular mucin is acceptable Adenocarcinoma ex GCC, Goblet cells or signet ring cells signet-ring-cell type arranged in irregular large clusters (group B) and sheets Single cell-infiltrating pattern Significant cytologic atypia Reduced intracellular mucin Marked desmoplasia Destruction of appendiceal wall Adenocarcinoma ex GCC, Requires at least focal evidence poorly differentiated of goblet cell morphology A (group C) component (>1 low-power field or 1 [mm.
Small tubules with blue mucin lined by a single cell and resembling signet ring cells may be seen (Figure 1, C).