castration cells

(redirected from signet ring cells)

cas·tra·tion cells

altered basophilic cells of the anterior lobe of the pituitary that develop following castration; the body of the cell is occupied by a large vacuole that displaces the nucleus to the periphery, giving the cell a resemblance to a signet ring.
Synonym(s): signet ring cells

cas·tra·tion cells

(kas-trā'shŭn selz)
Altered basophilic cells of the anterior lobe of the pituitary that develop following castration; the body of the cell is occupied by a large vacuole that displaces the nucleus to the periphery, giving the cell a resemblance to a signet ring.
Synonym(s): signet ring cells.
References in periodicals archive ?
According to Woodruff and Novak, Krukenberg's original criteria for this eponymous tumor were (i) tumor in the ovary, (ii) signet ring cells indicating intracellular mucin production, and (iii) sarcoma-like infiltration into the ovarian stroma.
Microscopically, the tumours showed diffuse infiltration by signet ring cells with surrounding zones of desmoplasia.
Signet ring cells are more frequently seen focally within otherwise high-grade prostate cancers and should be considered as part of the Gleason scoring.
Origin of Sample Histology 1 Lymph Adenocarcinoma, node solid 2 Primary Adenocarcinoma tumor with signet ring cells 3 Lymph Adenocarcinoma, solid node 4 Primary Adenocarcinoma tumor with signet ring cells 5 Brain Adenocarcinoma metastasis with signet ring cells 6 Primary Adenocarcinoma tumor with signet ring cells 7 Primary Adenocarcinoma, solid tumor 8 Lymph Adenocarcinoma, solid node 9 Lymph Adenocarcinoma node with signet ring cells 10 Pleural Adenocarcinoma metastasis 11 Primary Adenocarcinoma tumor Case No.
Cytologic criteria were Nuclear morphology (Large nuclei, Anisonucleosis, Hyperchromatic nuclei, Vesicular nuclei, Chromatin clumping, Prominent nucleoli, Multiple nucleoli), and Cellular morphology (Comet cells, Signet ring cells, Vacuolar cytoplasm, Granular cytoplasm, Apocrine cells, Ractive ductal cells, Squamous cells).
Mucinous and signet ring cells were more often identified (p=0.
Myxoid liposarcomas are as common as the welldifferentiated type; they are composed of proliferating lipoblasts at varying stages of differentiation, signet ring cells, a plexiform capillary pattern, and a myxoid matrix with nonsulfated glycosaminoglycans.
The tumor was composed of well-formed glands containing abundant mucin and signet ring cells.
Figure 8: Metastatic Signet ring cell carcinoma: HPE shows normal ovarian follicular lining with abundant signet ring cells infiltrating the stroma.
172) Other malignant tumors should be considered if signet ring cells are present: (1) poorly differentiated adenocarcinoma with focal signet ring cells; (2) squamous cell carcinoma with signet ring-like cells; (3) clear cell carcinoma with signet ring cells; and (4) metastatic signet-ring cell carcinoma (more often gastrointestinal and breast origin).