signal peptide


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signal peptide

a short sequence that directs PROTEINS to, and across, MEMBRANES. see LEADER PEPTIDE.
References in periodicals archive ?
In both cases, peptide hormone genes are initially translated as biologically inactive prepropeptides, followed by removal of the N-terminal signal peptide by a signal peptidase to afford a propeptides.
Short palate, lung and nasal epithelium clone 1 (SPLUNCl) is a secreted protein molecule, which is expressed highly on respiratory epithelium and has a signal peptide.
Pairwise alignment reveals that pneumolysin do not have the N-terminus signal peptide sequence which is present in the template i.
Moreover, a recent study reported that the BNP signal peptide derived from preproBNP also circulates in human blood and represents a potential biomarker for cardiac ischemia and myocardial infarction (8).
Closer examination of the HeCAl and HeCA2 sequences revealed that HeCA2 contained a signal peptide, but HeCAl contained no recognized signal-peptide domains (Fig.
These can be overcome by transferring the expressed protein to the periplasmic space with a suitable signal peptide.
The mature form of the hGH is created from its 217 amino acid precursor after removal of the signal peptide (26 amino terminal residues).
7% of the fully identified proteins) contained amino acids that formed part of a signal peptide (Fig.
The amino acid sequence of the G protein consisted of 669 aa and contained an N terminal signal peptide (1-MYHLIVLLVMLGQRAVA-17), a noncytoplasmic domain (aa 18-646), a transmembrane domain (647-ITAILMPLLSLAVVVGIIMCC-667), and a cytoplasmic tail of 2 aa, similar to other rhabdovirus G proteins as predicted by using Phobius and TMHMM (http://www.

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