siderophore


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siderophore

 [sid´er-o-for]
a macrophage containing hemosiderin.

sid·er·o·phore

(sid'er-ō-fōr),
1. A large extravasated mononuclear phagocyte containing granules of hemosiderin, found in the sputum or in the lungs of patients with longstanding pulmonary congestion from left ventricular failure.
See also: heart failure cell.
2. Secreted molecule which chelates iron.
Synonym(s): siderophage
[sidero- + G. phoros, bearing]

siderophore

/sid·ero·phore/ (sid´er-o-for″) a macrophage containing hemosiderin.

sid·er·o·phore

(sid'ĕr-ō-fōr)
A large, extravasated, mononuclear phagocyte containing granules of hemosiderin, found in the sputum or in the lungs of people with long-standingpulmonary congestion from left ventricular failure.
Synonym(s): siderophage.
[sidero- + G. phoros, bearing]

siderophore

a macrophage containing hemosiderin.
References in periodicals archive ?
S-649266 is a new parenteral siderophore cephalosporin antibiotic discovered by Shionogi & Co.
As in the case of fungi, the main mechanisms used by bacteria to weather minerals under aerobic conditions are acidification and chelation due to production of protons, organic acids and siderophores.
Much of the iron in ocean water is strongly bound to natural organic chelators, such as siderophores, which bind and release iron in different ways.
DFO is a siderophore produced by the fungus Streptomyces pilosus that has been used in clinical practice as a chelating agent for iron or aluminum overload.
Deferoxamine is a bacterial siderophore obtained from Streptomyces piloce that is used as a chelating agent in the treatment of acute iron toxicity and in chronic iron overload.
We know it is an effective siderophore and that it can make increased amounts of iron available from the soil to the rhizobia-plant symbiosis, which helps to make the heme protein in leghaemoglobin.
8, 2014 /PRNewswire/ --Findings reported at the 54th Interscience Conference on Antimicrobial Agents and Chemotherapy (ICAAC) showed Shionogi's novel parenteral siderophore cephalosporin, S-694266, to exhibit marked potency against Gram-negative bacteria listed by the Centers for Disease Control and Prevention (CDC) at the urgent or serious level including multidrug-resistant Pseudomonas(MDRP), MDR-Acinetobacter(MDRA) and carbapenem-resistant Enterobacteriaceae (CRE).
Plants in soils aerobic conditions have two strategy-oriented for access to the iron compounds: first siderophore secretion (non-protein amino acid) (This strategy is found in Gramineae family); and second separation iron of soil chelate or restore trivalent iron ([Fe.
Among the topics are recent trends in resistance to cell envelope-active antibacterial agents among key bacterial pathogens, viable screening targets related to the bacterial cell wall, the proliferation and significance of clinically relevant beta-lactamases, metallo-beta-lactamase structure and function, siderophore conjugates, and the role of the cell membrane and cell wall in mechanisms of daptomycin resistance in Staphylococcus aureus.
This fragment contains several open reading frames, including genes encoding aerobactin siderophore biosynthesis proteins.
Siderophore chelate iron and other metals also contribute to disease suppression by conferring a competitive advantage to biocontrol agent for the limited supply of essential trace minerals in natural habitats(4).
One of these rearrangements eliminates siderophore biosynthesis genes from ON-2010 and may compromise bacterial iron acquisition.