sickle cell retinopathy

sick·le cell ret·i·nop·a·thy

a condition marked by dilation and tortuosity of retinal veins and by microaneurysms and retinal hemorrhages; advanced stages may show neovascularization, vitreous hemorrhage, or retinal detachment.

proliferative sickle retinopathy

An ophthalmopathy which is the most severe ocular change in sickle cell disease, and linked to local hypoxia due to sludging of sickled cells within vessels. It is characterised by microaneurysms, tortuous retinal veins, haemorrhage, exudates, neovascularisation and, if extreme, retinal detachment.

Stages
▪ Stage I—Peripheral arteriolar occlusion, usually between equator and ora serrata.
▪ Stage II—Peripheral arteriolar-venular anastomoses, usually in temporal quadrant.
▪ Stage III—Neovascularisation, fibrous proliferatrion, vascular leakage, giving rise to seafan and sunburst pattern.
▪ Stage IV—Vitreous haemorrhage, commonly arising from neovascularisation.
▪ Stage V—Retinal detachment.

sick·le cell ret·i·nop·a·thy

(sik'ĕl sel ret'i-nop'ă-thē)
Ocular disorder marked by dilation and tortuosity of retinal veins, and by microaneurysms and retinal hemorrhages; advanced stages may show neovascularization, vitreous hemorrhage, or retinal detachment.
References in periodicals archive ?
These changes can be broadly split into two groups: non-proliferative sickle cell retinopathy (NPSR); and proliferative sickle cell retinopathy (PSR).
The development of sickle cell retinopathy is usually insidious with few visual symptoms in the early stages.
In this ongoing study, patients are being treated for various retinal conditions, including proliferative diabetic retinopathy, proliferative diabetic retinopathy with vitreous hemorrhage, diabetic macular edema, branch retinal vein occlusion with macular edema, sickle cell retinopathy, Coat's disease, acute retinal tears and post-op tears on sclearal buckles.
Idiopathic juxtafoveolar retinal telangiectasis (IRT) must be differentiated from other systemic and ocular diseases associated with telangiectasias like diabetic retinopathy, retinal vascular occlusions, Eale's disease, retinopathy of prematurity, or sickle cell retinopathy.

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