sicca complex

sic·ca com·plex

dryness of the mucous membranes, as of the eyes and mouth, in the absence of a connective tissue disease such as rheumatoid arthritis.

sicca complex

[sik′ə]
abnormal dryness of the mouth, eyes, or other mucous membranes. The condition is seen in patients with Sjögren's syndrome, sarcoidosis, amyloidosis, and deficiencies of vitamins A and C.

sicca complex

The constellation of symptoms related to generalised mucosal drying, which is most often associated with Sjögren syndrome but may occur in amyloidosis, haemochromatosis, hyperlipoproteinaemia types IV and V, sarcoidosis, vitamin C and/or A deficiency, scleroderma, and other connective tissue diseases.

Targeted tissues
• Eyes—xeroconjunctivitis due to decreased tears; thick, “ropy” secretions on the inner canthus; foreign body (tired, itchy, sandy) sensation; and decreased visual acuity. 
• Mouth—xerostomia with decreased salivation due to lymphocyte infiltration and duct obstruction, with soreness, adhesion of food to mucosa, “dry cracker” sign, angular cheilitis, fissuring of the tongue, and acceleration of caries.

sicca complex

Symptoms related to generalized mucosal drying, affecting Eyes–xeroconjunctivitis due to ↓ tears, thick, 'ropy' secretions on the inner canthus, foreign body–tired, itchy, sandy sensation, ↓ visual acuity Mouth–xerostomia with ↓ salivation due to lymphocyte infiltration and duct obstruction, with soreness, adhesion of food to mucosa, 'cracker' sign, angular cheilitis, lingual fissuring, acceleration of caries. See Dry eye, Dry mouth.

sic·ca com·plex

(sik'ă kom'pleks)
Dryness of the mucous membranes, as of the eyes and mouth, in the absence of a connective tissue disease such as rheumatoid arthritis.

sic·ca com·plex

(sik'ă kom'pleks)
Dryness of mucous membranes, as of eyes and mouth, in the absence of a connective tissue disease.
References in periodicals archive ?
Neuropathy is also associated with Sjogren syndrome, and peripheral neuropathy was more commonly reported in RA patients with Sjogren syndrome or sicca complex (22).
The hallmark of Sjogren's syndrome is the sicca complex of xerostomia and keratoconjunctivitis.