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short-acting insulin

   Also found in: Dictionary/thesaurus, Encyclopedia, Wikipedia 0.01 sec.
short-acting insulin,
a clear preparation of regular (crystalline zinc) insulin with an immediate (15 to 30 minutes) onset of action that reaches a peak of action in 2 to 4 hours. The duration of action is 6 to 8 hours. There is considerable variation in individual patients and with different doses in the same patient. Therefore these data should be considered only as rough guidelines. Also called rapid-acting insulin. Compare intermediate-acting insulin, long-acting insulin. See also insulin.

insulin (obtained from beef or pork, or human recombinant technology),
n brand names: Velosulin, Humulin R, Novolin R, Lente Insulin;
drug class: exogenous insulin, antidiabetic;
action: decreases blood glucose; important in regulation of fat and protein metabolism;
uses: ketoacidosis; type 1 and type 2 diabetes mellitus; hyperkalemia; hyperalimentation.
insulin, exogenous
n a type that comes from a source external to a diabetic patient's body, taken to offset the patient's natural deficiency of insulin.
insulin, intermediate-acting,
n a type that is a medium between rapid-acting and long-acting insulins; the onset is not as fast as rapid-acting insulin, but it reaches its peak action over a 4- to 12-hour period.
insulin, Lente
n.pr an intermediate-acting type that reaches its peak action over a 4- to 12-hour period.
insulin, Lispro,
n.pr a rapid-acting type that reaches its peak action in 30 to 90 minutes.
insulin, long-acting,
n a type that has a slow onset but reaches its peak action from 12 to 16 hours after administration.
insulin, NPH,
n a synthetic type used to treat diabetes. Classified as intermediate acting; peak action occurs 4 to 10 hours after administering.
insulin, rapid-acting,
n a synthetic type of insulin used to treat diabetes. Reaches peak action 30 to 90 minutes after administering.
insulin, regular,
n a synthetic type used to treat diabetes. Classified as short acting; peak action occurs 2 to 3 hours after administering.
insulin resistance,
n a complication of diabetes mellitus characterized by a need for more than 200 units of insulin per day to control hyperglycemia and ketosis. The cause is associated with insulin binding by high levels of antibody.
insulin shock,
insulin, short-acting,
n a synthetic type used to treat diabetes. Reaches peak action 2 to 3 hours after administering. Also called
regular insulin.
insulin, ultralente
n a synthetic type used to treat diabetes. Classified as long acting, with peak action occurring 12 to 16 hours after administering.


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The researchers have revealed that no difference was found between the short-acting insulin analogues, lispro and aspart, and human insulin.
The long-acting insulins are used for a basal insulin effect (a little insulin every so many minutes), with doses (called "boluses") of short-acting insulin given prior to each meal or large snack.
Glufast(R), a rapid onset and short-acting insulin secretagogue, was launched in 2004; Salagen(R), a therapeutic agent for dry mouth induced by radiation therapy for head and neck cancer was introduced in 2005; and Urief(R), used for the treatment of dysuria associated with benign prostatic hyperplasia (BPH), was put on the market in 2006.
 
 
 
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