shocking dose

shock·ing dose

in experimental anaphylaxis, the inoculum of antigen that causes anaphylactic shock in an animal sensitized by a previous inoculum (sensitizing dose) of the same antigen.
References in periodicals archive ?
But the most insidious deficiency of all may prove to be the onset of the "donut hole" or coverage gap, which could bring a shocking dose of reality to patients forced to pay full price for their drugs.
Here's your very first look at the Cairns, a family of five who are set to bring a shocking dose of sex and strife to Emmerdale as they topple soap's worst clan the Dingles.
BATTLE IN HEAVEN (18, 98mins) is a strange but compulsive Mexican film that opens and closes with explicit sex scenes, is punctuated with odd, almost surreal moments and has a shocking dose of unexpected violence.