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shiga-like toxins

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shiga-like toxins
toxins produced by certain strains of Escherichia coli which disrupt the function of the ribosome. Responsible for the lesions seen in edema disease in pigs, hemolytic uremic syndrome in humans and dogs. Called also verotoxin and vero cytotoxin.


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Pseudomonas aeruginosa can cause false-positive identification of verotoxin (Shiga-like toxin) production by a commercial enzyme immune assay system for the detection of Shiga-like toxins (SLTs).
These toxins are designated as verocytotoxins because of their toxic effects on cultured Vero cells or Shiga-like toxins because of their similarity to the cytotoxin produced by Shigella dysentery type 1.
 
 
 
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