lobata germacranolide sesquiterpene lactones
are described by McKinnon et al.
Thus atractylenolide I was isolated and investigated additionally to the above mentioned analogues, to gain first insights in the structure-activity relationship between these three sesquiterpene lactones
vulgare was identified as the sesquiterpene lactone
, 4[alpha],5[beta]-epoxy-germacra-l-(10),11(13)-dien-12,6[alpha]-olide (parthenolide), as previously described (Tiuman etal.
annua, to a great extent, might be contributed by lipophilic sesquiterpene lactones
of the extract.
Except for compound 1 (diversin), which is a terpenoid coumarin, all of the compounds (2-5) tested in this study belong to the class of sesquiterpene lactones
This plant, rich in flavonoids and sesquiterpene lactones
could be a good source of medicinal plants.
The drug has been tested phytochemically only by a few researchers; it contains several sesquiterpene lactones
, flavonoids and [gamma]-lactones, vitamin C (in fresh offshoots), etc (Adekenov et al.
patent #5,905,089, entitled "Use of sesquiterpene lactones
for treatment of severe inflammatory disorders.
are the most common allergens from Compositae.
Genus: a Review of Bioactive Sesquiterpene Lactones
Therapeutic effects are generally attributed to leaves and/or flowers mainly due to the presence of sesquiterpene lactones
and flavonoids (Pareek et al.
Some of the useful constituents found in arnica are flavonoids, polysaccharides, and sesquiterpene lactones