serum concentration

serum concentration

The amount of a drug or other compound in the circulation, both bound to proteins and unbound, the latter of which generally corresponds to the therapeutically active fraction.

serum concentration

Therapeutics The amount of a drug or other compound in the circulation, both bound to proteins and unbound, the latter of which generally corresponds to the theraepeutically active fraction
References in periodicals archive ?
The mean peak serum concentration, the time to reach mean peak serum concentration, total clearance, concentration at time zero, volume of distribution, terminal elimination rate constant, elimination half-life, total area under serum concentration-time curve were measured.
Independent sample t-test depicted that serum concentrations of Zn and Mn were decreased while serum concentration of Cu increased significantly in the lung cancer patient group.
Normal serum sodium is between 135-145 mEq/L, whereas hyponatremia is defined as a serum concentration less than 135 mEq/dL(4); symptoms often arise as the serum concentration falls below 130 mEq/L.
Association between maternal serum concentration of the DDT metabolite DDE and preterm and small-for-gestational-age babies at birth.
It is generally believed that serum concentration of IGF-1 is controlled by food intake, however, the effects of specific nutrients on serum IGF-1 have not been sufficiently studied.
It would be exciting if long-term survivors have higher serum concentration than rapid progressors," says Kurth.
The major advantage of PCA is in maintaining a minimum effective analgesic serum concentration without producing toxicity and/or recurrence of pain.
Researchers concluded that black tea consumption significantly lowered serum concentration of LDL cholesterol, especially in subjects with higher cardiovascular risk.
Salicylate Serum concentration should be used in conjunction
Compared with placebo, active treatment reduced the mean serum concentration of bioavailable testosterone by 25% (p < 0.
This serum concentration is much greater than the IOM's target of "sufficient" levels (defined as greater than 30 nmol/L).